Mechanisms and therapeutic targets of ischemic acute kidney injury
نویسندگان
چکیده
منابع مشابه
Cytokines and chemokines as therapeutic targets for ischemic kidney injury
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Acute kidney injury (AKI) is a common complication during inpatient hospitalization, and clinical outcomes remain poor despite advancements in renal replacement therapy. AKI in the setting of multiple organ failure (MOF) remains a formidable challenge to clinicians and incurs an unacceptably high mortality rate. Kidney ischemia-reperfusion injury (IRI) incites a proinflammatory cascade and rele...
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متن کاملMechanisms of Acute Kidney Injury and Repair
The mechanisms involved in kidney injury and repair are complex. In this chapter, I will briefl y summarize various components of this complexity. There are many potential causes of acute kidney injury (AKI), and each has its own characteristics, but I will focus on overriding themes, recognizing that the importance of some mechanisms may be dependent on the factors leading to the development o...
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ژورنال
عنوان ژورنال: Kidney Research and Clinical Practice
سال: 2019
ISSN: 2211-9140
DOI: 10.23876/j.krcp.19.062